• Product NameApixaban
• Brief DescriptionInhibitors
• Purification99.54%
• Biological ActivityApixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.
• Target NameFactor Xa inhibitor
• CAS No. 503612-47-3
• Calculated MW 459.5
• Formulation C25H25N5O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:COC1=CC=C(C=C1)N1N=C(C(N)=O)C2=C1C(=O)N(CC2)C1=CC=C(C=C1)N1CCCCC1=O
  Pathways:Metabolism
  Receptor:Factor Xa (human); Factor Xa (rabbit)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 18 mg/mL (39.17 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pinto DJ, et al. J Med Chem. 2007, 50(22), 5339-5356.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting