• Product NameGenistein
• Brief DescriptionInhibitors
• Purification99.69%
• Biological ActivityGenistein(NPI 031L), a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.
• Target NameEGFR antagonist
• CAS No. 446-72-0
• Calculated MW 270.24
• Formulation C15H10O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:OC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
  Pathways:Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
  Receptor:EGFR
  Boling pt:
  Melting pt:297-298C
  Solubility:Ethanol: 2 mg/mL (7.4 mM); DMSO: 54 mg/mL (199.82 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Akiyama T, et al. J Biol Chem, 1987, 262(12), 5592-5595.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting