• Product NameTAK-063
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs.
• Target NamePDE inhibitor
• CAS No. 1238697-26-1
• Calculated MW 428.42
• Formulation C23H17FN6O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=CN(N=C(C2=CC=NN2C2=CC=CC=C2)C1=O)C1=C(F)C=C(C=C1)N1C=CC=N1
  Pathways:Metabolism
  Receptor:PDE10A
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kunitomo J, et al. J Med Chem. 2014 Nov 26;57(22):9627-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting