• Product NameAL082D06
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAL 082D06(D-06) is the first selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM, exhibits excellent selectivity against AR, PR, MR and ER(Ki > 10 uM).
• Target NameGR antagonist
• CAS No. 256925-03-8
• Calculated MW 409.91
• Formulation C23H24ClN3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CN(C)C1=CC=C(C=C1)C(C1=CC=C(C=C1)N(C)C)C1=C(Cl)C=CC(=C1)[N+]([O-])=O
  Pathways:Metabolism
  Receptor:Glucocorticoid Receptor
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Avenant C, et al. Mol Cell Endocrinol. 2010 Oct 7;327(1-2):72-88.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting