• Product NameNS6180
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.
• Target NamePotassium Channel inhibitor
• CAS No. 353262-04-1
• Calculated MW 323.33
• Formulation C16H12F3NOS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:FC(F)(F)C1=CC=CC(CN2C(=O)CSC3=CC=CC=C23)=C1
  Pathways:Membrane transporter/Ion channel
  Receptor:KCa3.1 channel
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Strobak D, et al. Br J Pharmacol. 2013 Jan;168(2):432-44.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting