• Product NameABT-751 (E7010)
• Brief DescriptionInhibitors
• Purification99.42%
• Biological ActivityABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.
• Target NameMicrotubule Associated inhibitor
• CAS No. 141430-65-1
• Calculated MW 371.41
• Formulation C18H17N3O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=CC=C(C=C1)S(=O)(=O)NC1=C(NC2=CC=C(O)C=C2)N=CC=C1
  Pathways:Cytoskeletal Signaling
  Receptor:microtubule
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 12 mg/mL (32.3 mM); DMSO: 74 mg/mL (199.24 mM)
  Appearance:Pink powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Meany HJ, et al. Pediatr Blood Y. 2010, 54(1), 47-54.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting