• Product NameRGFP 966
• Brief DescriptionInhibitors
• Purification99.85%
• Biological ActivityRGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC.
• Target NameHDAC inhibitor
• CAS No. 1357389-11-7
• Calculated MW 362.4
• Formulation C21H19FN4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC=C(C=C1)/C=C/CN2C=C(C=N2)/C=C/C(=O)NC3=C(C=C(C=C3)F)N
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Malvaez M, et al. PNAS, 2013, 110(7), 2647-2652.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting