• Product NameErastin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityErastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS.
• Target NameFerroptosis activator
• CAS No. 571203-78-6
• Calculated MW 547.04
• Formulation C30H31ClN4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CCOC1=CC=CC=C1N1C(=O)C2=CC=CC=C2N=C1C(C)N1CCN(CC1)C(=O)COC1=CC=C(Cl)C=C1
  Pathways:Cell Cycle/Checkpoint
  Receptor:Ferroptosis
  Boling pt:
  Melting pt:
  Solubility:DMSO: 19 mg/mL (34.73 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dolma S, et al. Y Cell. 2003, 3(3), 285-296.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting