• Product NameEmpagliflozin (BI 10773)
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityEmpagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6.
• Target NameSGLT inhibitor
• CAS No. 864070-44-0
• Calculated MW 450.91
• Formulation C23H27ClO7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
  Pathways:GPCR/G Protein
  Receptor:SGLT1; SGLT2; SGLT4; SGLT5; SGLT6
  Boling pt:
  Melting pt:
  Solubility:DMSO: 90 mg/mL (199.59 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Grempler R, et al. Diabetes Obes Metab, 2012, 14(1), 83-90.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting