• Product NameBMH-21
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBMH-21 is a small molecule DNA intercalator that binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription; does not cause phosphorylation of H2AX.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 896705-16-1
• Calculated MW 360.41
• Formulation C21H20N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CN(C)CCNC(=O)C1=CC=CN2C(=O)C3=CC4=CC=CC=C4C=C3N=C12
  Pathways:DNA Damage/DNA Repair
  Receptor:RNA polymerase I
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL warmed (5.54 mM); DMSO: 5 mg/mL warmed (13.87 mM)
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Colis L, et al. Oncotarget. 2014 Jun 30;5(12):4361-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting