• Product NameRo 48-8071 fumarate
• Brief DescriptionInhibitors
• Purification98.72%
• Biological ActivityRo 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
• Target NameOthers inhibitor
• CAS No. 189197-69-1
• Calculated MW 564.44
• Formulation C27H31BrFNO6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O
  Pathways:Others
  Receptor:Oxidosqualene cyclase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Morand OH, et al. J Lipid Res. 1997 Feb;38(2):373-90.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting