• Product NameGW 9508
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityGW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.
• Target NameGPR agonist
• CAS No. 885101-89-3
• Calculated MW 347.41
• Formulation C22H21NO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:OC(=O)CCC1=CC=C(NCC2=CC(OC3=CC=CC=C3)=CC=C2)C=C1
  Pathways:Endocrinology/Hormones
  Receptor:GPR120; GPR40(FFA1)
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 69 mg/mL (198.61 mM); DMSO: 69 mg/mL (198.61 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Briscoe CP, et al. Br J Pharmacol, 2006, 148(5), 619-628.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting