• Product NameCanagliflozin
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivityCanagliflozin(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.
• Target NameSGLT inhibitor
• CAS No. 842133-18-0
• Calculated MW 444.52
• Formulation C24H25FO5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
  Pathways:GPCR/G Protein
  Receptor:hSGLT2; mSGLT2; rSGLT2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 88 mg/mL (197.96 mM)
  Appearance:White Solid
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Liang Y, et al. PLoS One. 2012, 7(2), e30555.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting