• Product NamePalbociclib
• Brief DescriptionInhibitors
• Purification99.10%
• Biological ActivityPalbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
• Target NameCDK inhibitor
• CAS No. 571190-30-2
• Calculated MW 447.54
• Formulation C24H29N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N3CCNCC3)N=C2N(C2CCCC2)C1=O
  Pathways:Cell Cycle/Checkpoint
  Receptor:CDK4; CDK6
  Boling pt:
  Melting pt:
  Solubility:DMSO: > 10mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fry DW, et al. Mol Y Ther, 2004, 3(11), 1427-1438.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting