• Product NameObeticholic Acid
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityINT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.
• Target NameFXR agonist
• CAS No. 459789-99-2
• Calculated MW 420.63
• Formulation C26H44O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O
  Pathways:Metabolism
  Receptor:FXR
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 84 mg/mL warmed (199.7 mM); DMSO: 84 mg/mL (199.7 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pellicciari R, et al. J Med Chem. 2002, 45(17), 3569-3572.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting