- Product NameRegorafenib (BAY 73-4506)
- Brief DescriptionInhibitors
- Purification99.00%
- Biological ActivityRegorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively.
- Target Namec-Kit inhibitor; c-RET inhibitor; Raf inhibitor; VEGFR inhibitor
- CAS No. 755037-03-7
- Calculated MW 482.82
- Formulation C21H15ClF4N4O3
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;