• Product NameHPGDS-inhibitor-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityHPGDS inhibitor 1 is a novel and selective Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50 Value of 0.7 nM.
• Target NamePGE Synthase inhibitor
• CAS No. 1033836-12-2
• Calculated MW 381.37
• Formulation C19H19F4N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:FC1=CC=CC(=C1)C1=NC=C(C=C1)C(=O)NC1CCN(CC(F)(F)F)CC1
  Pathways:Immunology/Inflammation
  Receptor:hPGDS
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chris P. Carron, et al. ACS Med. Chem. Lett., 2010, 1 (2), pp 59-63

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting