• Product NameJW55
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityJW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively.
• Target NamePPAR inhibitor
• CAS No. 664993-53-7
• Calculated MW 434.48
• Formulation C25H26N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=CC=C(C=C1)C1(CNC(=O)C2=CC=C(NC(=O)C3=CC=CO3)C=C2)CCOCC1
  Pathways:Metabolism
  Receptor:TNKS1; TNKS2
  Boling pt:
  Melting pt:
  Solubility:DMSO, Ethanol: 100 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Waaler J, et al. Y Res. 2012 Jun 1;72(11):2822-32.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting