• Product NameZ-JIB-04 (NSC 693627)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityJIB-04 Z-isomer, also known as NSC 693627, is an isomer of JIB-04. JIB-04 is a Jumonji histone demethylase inhibitor. JIB-04 selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. JIB-04 can prolong survival in a mouse model of breast cancer.
• Target NameOthers inhibitor
• CAS No. 199596-24-2
• Calculated MW 308.76
• Formulation C17H13ClN4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC=C(C=C1)/C(=N/NC2=NC=C(C=C2)Cl)/C3=CC=CC=N3
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

N/A

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting