• Product NameTenovin-6
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTenovin-6 is a small molecule activator of p53 transcriptional activity.
• Target NameSirtuin inhibitor
• CAS No. 1011557-82-6
• Calculated MW 454.63
• Formulation C25H34N4O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)CCCCC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT1; SIRT2; SIRT3
  Boling pt:
  Melting pt:
  Solubility:Water: 98 mg/mL warmed (215.55 mM); DMSO: 98 mg/mL (215.55 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lain S, et al. Y Cell, 2008, 13(5), 454-463.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting