• Product NameNexturastat A
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM, >190-fold selectivity over other HDACs.
• Target NameHDAC inhibitor
• CAS No. 1403783-31-2
• Calculated MW 341.4
• Formulation C19H23N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCCCN(CC1=CC=C(C=C1)C(=O)NO)C(=O)NC1=CC=CC=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC6
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL (5.85 mM); DMSO: 68 mg/mL (199.17 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bergman JA, et al. J Med Chem. 2012, 55(22), 9891-9899.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting