• Product NameCK-636
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
• Target NameMicrotubule Associated inhibitor
• CAS No. 442632-72-6
• Calculated MW 284.38
• Formulation C16H16N2OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=C(CCNC(=O)C2=CC=CS2)C2=CC=CC=C2N1
  Pathways:Cytoskeletal Signaling
  Receptor:Arp2/3 complex (Bovine); Arp2/3 complex (Fission yeast); Human Arp2/3 complex
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 50 mg/mL (175.82 mM); DMSO: 57 mg/mL (200.43 mM)
  Appearance:White Sheet Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Nolen BJ, et al. Nature. 2009 , 460(7258), 1031-1034.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting