• Product NameINK 128 (MLN0128)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityINK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms.
• Target NamemTOR inhibitor; PI3K inhibitor
• CAS No. 1224844-38-5
• Calculated MW 309.33
• Formulation C15H15N7O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)N1N=C(C2=C1N=CN=C2N)C1=CC2=C(OC(N)=N2)C=C1
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:mTOR; mTOR; PI3Kα; PI3Kγ; PI3Kδ
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 2 mg/mL (6.46 mM); DMSO: 62 mg/mL (200.43 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hsieh AC, et al. Nature. 2012, 485(7396), 55-61.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting