• Product NameXMD17-109
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityXMD17-109 is a novel, specific ERK-5 inhibitor with an EC50 4.2 uM in HEK293 cells.
• Target NameERK inhibitor
• CAS No. 1435488-37-1
• Calculated MW 638.81
• Formulation C36H46N8O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC1=C(NC2=NC=C3N(C)C(=O)C4=CC=CC=C4N(C4CCCC4)C3=N2)C=CC(=C1)C(=O)N1CCC(CC1)N1CCN(C)CC1
  Pathways:MAPK
  Receptor:ERK5
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (156.54 mM); DMSO: 100 mg/mL (156.54 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Denq X, et al. Eur J Med Chem. 2013, 70, 758-767.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting