• Product NameXMD8-92
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityXMD8-92 is a potent and selective BMK1/ERK5 inhibitor with Kd of 80 nM.
• Target NameBMI-1 inhibitor
• CAS No. 1234480-50-2
• Calculated MW 474.55
• Formulation C26H30N6O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC1=C(NC2=NC=C3N(C)C(=O)C4=CC=CC=C4N(C)C3=N2)C=CC(=C1)N1CCC(O)CC1
  Pathways:Others
  Receptor:BMI-1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 73 mg/mL warmed (153.82 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sureban SM, et al. Y Lett. 2014 , 351(1), 151-161.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting