• Product NameDynasore
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase.
• Target NameDynamin inhibitor
• CAS No. 304448-55-3
• Calculated MW 322.31
• Formulation C18H14N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1=CC=C2C=C(C(=CC2=C1)C(=O)NN/C=C/3\C=CC(=O)C(=C3)O)O
  Pathways:Cytoskeletal Signaling
  Receptor:Dynamin1/2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 64 mg/mL (198.56 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Macia E, et al. Dev Cell, 2006, 10(6), 839-850.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting