• Product NameNMS 873
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityNMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
• Target Namep97 inhibitor
• CAS No. 1418013-75-8
• Calculated MW 520.67
• Formulation C27H28N4O3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=C(C=CC(OCC2=NN=C(SC3CCCC3)N2C2=CN=CC=C2)=C1)C1=CC=C(C=C1)S(C)(=O)=O
  Pathways:Ubiquitination
  Receptor:p97
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100 mg/mL (192.06 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Magnaghi P, et al. Nat Chem Biol. 2013, 9(9), 548-556.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting