• Product NameS1RA
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityS1RA(E-52862) is a potent and selective sigma-1 receptor(1R, Ki=17 nM) antagonist, showed good selectivity against 2R (Ki > 1000 nM).
• Target NameSigma receptor antagonist
• CAS No. 878141-96-9
• Calculated MW 337.42
• Formulation C20H23N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1=CC(OCCN2CCOCC2)=NN1C1=CC2=CC=CC=C2C=C1
  Pathways:GPCR/G Protein
  Receptor:σ1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Daz JL, et al. J Med Chem. 2012 Oct 11;55(19): 8211-24.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting