• Product NamePPQ-102
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC 50approximately 90 nM.
• Target NameCFTR inhibitor
• CAS No. 931706-15-9
• Calculated MW 438.48
• Formulation C26H22N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CN1C2=C3C(NC4=CC=CC=C4N3C(=C2C(=O)N(C)C1=O)C1=CC=CC=C1)C1=CC=C(C)O1
  Pathways:Membrane transporter/Ion channel
  Receptor:CFTR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 5 mg/mL
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tradtrantip L, et al. J Med Chem. 2009 Oct 22;52(20):6447-55.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting