• Product NameAtglistatin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAtglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with an?IC50?of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.
• Target NameLipase inhibitor
• CAS No. 1469924-27-3
• Calculated MW 283.37
• Formulation C17H21N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN(C)C(=O)NC1=CC=CC(=C1)C1=CC=C(C=C1)N(C)C
  Pathways:Metabolism
  Receptor:ATGL
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 4 mg/mL (14.11 mM); DMSO: 57 mg/mL (201.15 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Mayer N, et al. Nat Chem Biol. 2013, 9(12), 785-787.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting