• Product NameLH-846
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); displays no inhibitory activity at CK2.
• Target NameCasein Kinase inhibitor
• CAS No. 639052-78-1
• Calculated MW 316.81
• Formulation C16H13ClN2OS
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC1=CC2=C(C=C1Cl)N=C(NC(=O)CC1=CC=CC=C1)S2
  Pathways:Metabolism; Stem Cells
  Receptor:CK1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 45 mg/mL
  Appearance:Purple Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lee JW, et al. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting