• Product NameNSC 405020
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNSC 405020 is a noncatalytic inhibitor of MT1-MMP, directly interacts with PEX domain of MT1-MMP, affects PEX homodimerization but not catalytic activity of MT1-MMP.
• Target NameMMP inhibitor
• CAS No. 7497-7-6
• Calculated MW 260.16
• Formulation C12H15Cl2NO
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCCC(C)NC(=O)C1=CC(Cl)=C(Cl)C=C1
  Pathways:Proteases/Proteasome
  Receptor:MT1-MMP
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 52 mg/mL (199.87 mM); DMSO: 52 mg/mL (199.87 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Remacle AG, et al. Y Res. 2012 May 1;72(9):2339-49.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting