• Product NameRo 61-8048
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityRo 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 of 37 nM.
• Target NameHydroxylase inhibitor
• CAS No. 199666-03-0
• Calculated MW 421.45
• Formulation C17H15N3O6S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=C(OC)C=C(C=C1)S(=O)(=O)NC1=NC(=CS1)C1=CC(=CC=C1)[N+]([O-])=O
  Pathways:Metabolism
  Receptor:KMO; KMO
  Boling pt:
  Melting pt:
  Solubility:DMSO: 59 mg/mL
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cao ZX, et al. Cell Physiol Biochem. 2011;27(5):565-74.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting