• Product NamePyridostatin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 1085412-37-8
• Calculated MW 596.64
• Formulation C31H32N8O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:NCCOC1=CC(=NC(=C1)C(=O)NC1=NC2=CC=CC=C2C(OCCN)=C1)C(=O)NC1=NC2=CC=CC=C2C(OCCN)=C1
  Pathways:DNA Damage/DNA Repair
  Receptor:G-quadruplexe
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 30 mg/mL 30; Water: 100 mg/mL 100; DMSO: 100 mg/mL 100
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Murat P, et al. Nat Chem Biol. 2014, 10(5), 358-364.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting