• Product NameMdivi 1
• Brief DescriptionInhibitors
• Purification98.07%
• Biological ActivityMdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM.
• Target NameDynamin inhibitor
• CAS No. 338967-87-6
• Calculated MW 353.22
• Formulation C15H10Cl2N2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=C(Cl)C=C(Cl)C(=C1)N1C(=S)NC2=CC=CC=C2C1=O
  Pathways:Cytoskeletal Signaling
  Receptor:Dnm1 GTPase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 70 mg/mL (198.17 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cassidy-Stone A, et al. Dev Cell, 2008, 14(2), 193-204.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting