• Product NameMHY1485
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivityMHY1485 is a mTOR activator; inhibits the autophagic process by inhibition of fusion between autophagosomes and lysosomes leading to the accumulation of LC3II protein and enlarged autophagosomes.
• Target NamemTOR activator
• CAS No. 326914-06-1
• Calculated MW 387.39
• Formulation C17H21N7O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:[O-][N+](=O)C1=CC=C(NC2=NC(=NC(=N2)N2CCOCC2)N2CCOCC2)C=C1
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:mTOR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 33 mg/mL (85.18 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Choi YJ, et al. PLoS One. 2012, 7(8), e43418.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting