• Product NameBRD4770
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBRD4770 is a histone methyltransferase G9a inhibitor with IC50 of 6.3 μM, and induces cell senescence.
• Target NameHistone Methyltransferase inhibitor
• CAS No. 1374601-40-7
• Calculated MW 413.47
• Formulation C25H23N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC(=O)C1=CC2=C(C=C1)N(CCCC1=CC=CC=C1)C(NC(=O)C1=CC=CC=C1)=N2
  Pathways:Chromatin/Epigenetic
  Receptor:G9a
  Boling pt:
  Melting pt:
  Solubility:DMSO: 27 mg/mL warmed (65.3 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yuan Y, et al. ACS Chem Biol. 2012, 7(7), 1152-1157.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting