• Product Name6H05
• Brief DescriptionInhibitors
• Purification99.00%
• Biological Activity6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
• Target NameRaf inhibitor
• CAS No. 1469338-01-9
• Calculated MW 590.14
• Formulation C20H30ClN3O2S3CF3COOH
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(=O)C(F)(F)F.CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC1=CC=C(Cl)C=C1
  Pathways:MAPK
  Receptor:K-Ras(G12C)
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO, Water, Ethanol
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ostrem JM, et al. Nature. 2013, 503(7477), 548-551.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting