• Product NameB-AP15
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityB-AP15(NSC687852) is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
• Target NameDUB inhibitor
• CAS No. 1009817-63-3
• Calculated MW 419.39
• Formulation C22H17N3O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C=CC(=O)N1C/C(=C\C2=CC=C(C=C2)[N+](=O)[O-])/C(=O)/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C1
  Pathways:Ubiquitination
  Receptor:UCH-L5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 48 mg/mL warmed (114.45 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. D'Arcy P, et al. Nat Med. 2011 Nov 6;17(12):1636-40.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting