• Product NameNVP 231
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNVP-231 is a potent, specific, and reversible CerK inhibitor(IC50=122 nM) that competitively inhibits binding of ceramide to CerK.
• Target NameERK inhibitor
• CAS No. 362003-83-6
• Calculated MW 431.55
• Formulation C25H25N3O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:O=C(NC1=NC2=C(S1)C=C(NC(=O)C13CC4CC(CC(C4)C1)C3)C=C2)C1=CC=CC=C1
  Pathways:MAPK
  Receptor:CERK
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Graf C, et al.Mol Pharmacol. 2008 Oct;74(4):925-32.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting