• Product NameBay 11-7085
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM.
• Target NameIκB/IKK inhibitor
• CAS No. 196309-76-9
• Calculated MW 249.33
• Formulation C13H15NO2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N
  Pathways:NF-κb
  Receptor:IκBα?phosphorylation
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 50 mg/mL (200.53 mM); DMSO: 50 mg/mL (200.53 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pierce JW, et al. J Biol Chem. 1997, 272(34), 21096-21103.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting