• Product NameGSK3787
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityGSK3787 is as a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ.
• Target NamePPAR inhibitor
• CAS No. 188591-46-0
• Calculated MW 392.78
• Formulation C15H12ClF3N2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:FC(F)(F)C1=CN=C(C=C1)S(=O)(=O)CCNC(=O)C1=CC=C(Cl)C=C1
  Pathways:Metabolism
  Receptor:PPARδ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 79 mg/mL (201.13 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shearer BG, et al. J Med Chem, 2010, 53(4), 1857-1861.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting