• Product NameBS-181
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. ; >40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
• Target NameCDK inhibitor
• CAS No. 1092443-52-1
• Calculated MW 380.53
• Formulation C22H32N6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC(C)C1=C2N=C(NCCCCCCN)C=C(NCC3=CC=CC=C3)N2N=C1
  Pathways:Cell Cycle/Checkpoint
  Receptor:CDK7
  Boling pt:
  Melting pt:
  Solubility:DMSO: 80mg/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ali S, et al. Y Res. 2009 Aug 1;69(15): 6208-15.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting