• Product NameAsenapine Maleate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDeveloped by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
• Target Name5-HT Receptor antagonist
• CAS No. 85650-56-2
• Calculated MW 401.84
• Formulation C21H20ClNO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1C[C@H]2[C@H](C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24.C(=C\C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2A; 5-HT2B; 5-HT2C; 5-HT6; 5-HT7
  Boling pt:
  Melting pt:
  Solubility:DMSO: 80 mg/mL (199.08 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shahid M, et al. J Psychopharmacol. 2009 Jan;23(1):65-73.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting