• Product NameTubastatin A BASE
• Brief DescriptionInhibitors
• Purification98.18%
• Biological ActivityTubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8.
• Target NameHDAC inhibitor
• CAS No. 1252003-15-8
• Calculated MW 335.4
• Formulation C20H21N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CN1CCC2=C(C1)C1=CC=CC=C1N2CC1=CC=C(C=C1)C(=O)NO
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC6
  Boling pt:
  Melting pt:
  Solubility:DMSO: 9 mg/mL (26.83 mM)
  Appearance:White Crystalline Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Butler KV, et al. J Am Chem Soc, 2010, 132(31), 10842-10846.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting