• Product NameUNC2250
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityUNC2250 is a potent and selective Mer inhibitor with IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3.
• Target NameTAM Receptor inhibitor
• CAS No. 1493694-70-4
• Calculated MW 440.58
• Formulation C24H36N6O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCCCNC1=NC=C(C(NC2CCC(O)CC2)=N1)C1=NC=C(CN2CCOCC2)C=C1
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:AXL; Mer; Tyro3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 2 mg/mL warmed (4.53 mM)
  Appearance:Yellow Solid
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang W, et al. J Med Chem. 2013, 56(23), 9683-9692.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting