• Product NameDBEQ
• Brief DescriptionInhibitors
• Purification99.15%
• Biological ActivityDBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM.
• Target Namep97 inhibitor
• CAS No. 177355-84-9
• Calculated MW 340.42
• Formulation C22H20N4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C(NC1=NC2=CC=CC=C2C(NCC2=CC=CC=C2)=N1)C1=CC=CC=C1
  Pathways:Ubiquitination
  Receptor:p97
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 5 mg/mL (14.68 mM); DMSO: 68 mg/mL (199.75 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chou TF, et al. Proc Natl Acad Sci U S A, 2011, 108(12), 4834-4839.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting