• Product NameGW 627368X
• Brief DescriptionInhibitors
• Purification99.92%
• Biological ActivityGW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).
• Target NameProstaglandin Receptor antagonist
• CAS No. 439288-66-1
• Calculated MW 544.62
• Formulation C30H28N2O6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC1=C2CN(C(=O)C2=C(OCC)C2=CC=CC=C12)C1=CC=C(CC(=O)NS(=O)(=O)C2=CC=CC=C2)C=C1
  Pathways:GPCR/G Protein
  Receptor:EP4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mg/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wilson RJ, et al. Br J Pharmacol. 2006 Jun; 148(3): 326-39.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting