• Product NameHA14-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityHA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.
• Target NameBcr-Abl inhibitor
• CAS No. 65673-63-4
• Calculated MW 409.23
• Formulation C17H17BrN2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CCOC(=O)C(C#N)C1C2=C(OC(N)=C1C(=O)OCC)C=CC(Br)=C2
  Pathways:Angiogenesis; Cytoskeletal Signaling
  Receptor:Bcl-2
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 82 mg/mL (200.37 mM); DMSO: 82 mg/mL (200.37 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang JL, et al. Proc Natl Acad Sci, 2000, 97(13), 7124-7129.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting