• Product NameTriapine
• Brief DescriptionInhibitors
• Purification99.75%
• Biological ActivityTriapine(NSC663249; OCX191; PAN-811) is a ribonucleotide reductase inhibitor, has been extensively evaluated in clinical trials in the last decade; CDK inhibtor.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 143621-35-6
• Calculated MW 195.24
• Formulation C7H9N5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=CC(=C(N=C1)/C=N/NC(=S)N)N
  Pathways:DNA Damage/DNA Repair
  Receptor:RR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 47 mg/mL
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Trondl R, et al. Mol Pharmacol. 2014 Mar;85(3):451-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting